Diagnosis of Barrett’s Oesophagus

Barrett’s oesophagus (Columnar lined oesophagus)-Normal squamous lining has been replaced by a metaplastic columnar epithelium which is visible macroscopically. In order to make a positive diagnosis of “Barrett’s oesophagus”, a segment of columnar metaplasia of any length must be visible endoscopically above the oesophago-gastric junction and confirmed or corroborated histologically.

  • Diagnostic of CLO – Native oesophageal structures with metaplastic glandular mucosa, +/-intestinal metaplasia.

  • Biopsies corroborative of an endoscopic diagnosis of CLO – Intestinalised metaplastic glandular mucosa with no evidence of native oesophageal structures. This could potentially still represent incomplete intestinal metaplasia in the stomach, especially in a hiatus hernia or IM at the cardia.
  • Biopsies in keeping with, but not specific for CLO- Gastric type mucosa of either fundic or cardic type without IM. Patchwork appearance is still possible, as is a non-organised arrangement. Such appearances could, however, represent the OG junction or the stomach, with or without hiatal hernia.
  • Biopsies without evidence of CLO – Oesophageal type squamous mucosa with no evidence of glandular epithelium.


British Society of Gastroenterology. Guidelines for the diagnosis and management of columnar lined Barrett’s oesophagus.

This entry was posted in Gastrointestinal. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s