Monthly Archives: November 2012

Approach to Vesiculo-bullous Disorders

When assessing vesiculo-bullous diseases first assess the anatomic level of split. Then an assessment of the mechanisms of split may be helpful; whether the process appears spongiotic, acantholytic or if there is ballooning degeneration of keratinocytes. For subepidermal blisters then … Continue reading

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Painful skin tumours

Came across the mneumonic today for the differentials of painful skin tumours: LEND AN EGG Leiomyoma Eccrine spiradenoma Neuroma Dermatofibroma Angiolipoma Neurilemmoma Endometrioma Glomus tumor Granular cell tumour Reference: Naverson et al. Painful tumours of the skin: “LEND AN EGG”. … Continue reading

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Passed the Part 1 🙂 Woo!

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Urothelial Transitional Cell Carcinoma

Histological grade is one of the most important prognostic factors in bladder Ca. The 1973 WHO classification: Papilloma Grade I  – Minimal architectural abnormality and cytological atypia. Greater than 7 urothelial cells thick, predilection for ureteric orifices. Increased risk of … Continue reading

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Mature Cystic Teratomas (Dermoid Cysts)

Near full house of different tissues seen in dermoid cysts in the last week:

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Assessing Leiomyomas

Leiomyomas are very common and show a fascicular arrangement of smooth muscle bundles. However there are a number of variants, atypical features, degenerative changes and treatment associated changes worth looking out for. Cellular leiomyoma – Look much more blue, as … Continue reading

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Barrett’s Surveillance

Dysplasia in Barrett’s may be classified as indefinite, low grade or high grade. I looked at an interesting case today which showed nuclear atypia with enlarged overlapping nuclei, mitoses and loss of surface maturation. But it was clearly focal and … Continue reading

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